Okihide Hikosaka is a neuroscience research professor who specializes in the mechanisms of motivation, learning, skill…
Okihide Hikosaka is a neuroscience research professor who specializes in the mechanisms of motivation, learning, skill, decision-making, attention, and oculomotor control. His research into neuronal mechanisms of voluntary behavior and basal ganglia function created breakthroughs in the understanding of the neurochemistry behind information-seeking behavior and the efficacy of grouping motor sequence learning actions (otherwise known as “chunking”) in order to remember more than individual actions. Hikosaka’s research proved that the brain is chemically wired to be rewarded with dopamine for learning information about the future. “This result supports the notion that midbrain dopamine neurons are coding for both primitive and cognitive rewards. So why do dopamine neurons treat information as a reward? It’s easy to see how treating information this way might be a useful evolutionary adaptation. For many animals, each day consists of numerous decisions that pertain to eating, reproducing and socializing. Obviously, having access to more relevant information – such as knowing where the food is located - allows animals to make better decisions. Furthermore, having access to such information might give us better control over our environment, thus increasing our chances of survival.” Hikosaka's research impacts the understanding of drug abuse, Parkinson’s and many other aspects of behavior and brain function and dysfunction.
Famous People from Nagano Prefecture
Nagano Prefecture: 2 people
Minoru Shirota (代田 稔, Shirota Minoru; 23 April 1899 – 10 March 1982) was a Japanese microbiologist who made pioneering…
Minoru Shirota (代田 稔, Shirota Minoru; 23 April 1899 – 10 March 1982) was a Japanese microbiologist who made pioneering research on gut microbiota and developed the first commercial probiotic. In the 1930, he identified a strain of lactic acid bacteria that is part of normal gut flora that he originally called Lactobacillus casei Shirota, which appeared to help contain the growth of harmful bacteria in the gut. The species was later reclassified as Lactobacillus paracasei. Using his novel bacterium, Shirota produced the first probiotic yogurt, named Yakult in 1935. The commercial success of the beverage led to the establishment of the company Yakult Honsha and its subsidiary research organisation Yakult Central Institute in 1935.